HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Factor XII and partial prekallikrein deficiencies in a dog with recurrent gastrointestinal hemorrhage.

Abstract
Factor XII deficiency and impaired prekallikrein activity were diagnosed in a 1-year-old Chinese Shar Pei. The dog experienced repeated episodes of intestinal hemorrhage and diarrhea. Laboratory findings were compatible with blood loss (iron deficiency anemia and hypoproteinemia). Necropsy findings suggested mild infiltrative bowel disease that could have been responsible for the dog's diarrhea, but no explanation for the severe recurrent gastrointestinal hemorrhage could be found. Factor XII deficiency is uncommon in the dog and is not associated with hemorrhagic tendencies. The factor XII deficiency in this case may have contributed to the gastrointestinal hemorrhage.
AuthorsC M Otto, W J Dodds, C E Greene
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 198 Issue 1 Pg. 129-31 (Jan 01 1991) ISSN: 0003-1488 [Print] United States
PMID1995570 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Prekallikrein
Topics
  • Animals
  • Breeding
  • Diarrhea (complications, etiology, veterinary)
  • Dog Diseases (etiology)
  • Dogs
  • Factor XII Deficiency (complications, veterinary)
  • Gastrointestinal Hemorrhage (etiology, veterinary)
  • Male
  • Prekallikrein (deficiency)
  • Recurrence

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: