Abstract | OBJECTIVE: METHODS: RESULTS: The median follow-up was 62 months. The effective rate was 72.3% in the thymectomy group and 34.3% in the medication group (P < 0.01). The COX regression analysis revealed that the prognosis was statistically independent of Titin Ab (P < 0.05), thymus pathology (P < 0.05) and prednisone treatment (P < 0.05). The rate of relapse (Log-Rank, P < 0.05) and the rate of conversion (Log-Rank, P < 0.05) were smaller in the thymectomy group than in the medication groups. The rates of relapse and conversion in OMG with Titin Ab positive or thymomas were higher than OMG with Titin Ab negative or non- thymomas (Log-Rank, P < 0.05). CONCLUSION: As an effective and safe treatment for OMG, thymectomy can relieve the symptoms and prevent the progression of OMG to GMG.
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Authors | Yan Deng, Xu Zhang |
Journal | Zhonghua yi xue za zhi
(Zhonghua Yi Xue Za Zhi)
Vol. 89
Issue 27
Pg. 1922-5
(Jul 21 2009)
ISSN: 0376-2491 [Print] China |
PMID | 19953918
(Publication Type: English Abstract, Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Female
- Humans
- Male
- Middle Aged
- Myasthenia Gravis
(diagnosis, surgery)
- Prognosis
- Thymectomy
- Treatment Outcome
- Young Adult
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