[Axillary hyperhidrosis--efficacy and tolerability of an aluminium chloride antiperspirant. Prospective evaluation on 20 patients with idiopathic axillary hyperhidrosis].

Abstract

BACKGROUND:

The purpose of this study was to evaluate the efficacy and tolerability of aluminium chloride gel for treatment of axillary hyperhidrosis.

PATIENTS AND METHODS:

A total of 20 patients aged 22-38 (mean age: 26.9+/-4.3) with idiopathic axillary hyperhidrosis were included and treated with an antiperspirant (Sweat-off, Sweat-off GmbH, Hügelsheim). Study duration was 42 days. Treatment efficacy was evaluated clinically, as well as by starch-iodine test, gravimetric analysis and evaluation of the skin surface pH.

RESULTS:

After treatment there was a significant clinical improvement accompanied by significant qualitative and quantitative reduction of sweat as well as a significant reduction of skin surface pH. Except for slight skin irritation in 6 patients, there were no other side effects. Patient satisfaction improved markedly during the study.

CONCLUSION:

Treatment of axillary hyperhidrosis with aluminium chloride is an effective, safe and inexpensive treatment modality.

• Authors: M Streker, T Reuther, S Verst, M Kerscher
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 61 Issue 2 Pg. 139-44 (Feb 2010) ISSN: 1432-1173 [Electronic] Germany
• Vernacular Title: Hyperhidrosis axillaris--Effektivität und Verträglichkeit eines aluminiumchloridhaltigen Antiperspirants. Prospektive Evaluation an 20 Patienten mit idiopathischer Hyperhidrosis axillaris.
• PMID: 19953218 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Aluminum Compounds
• Antiperspirants
• Astringents
• Chlorides
• Aluminum Chloride

Topics

• Adult
• Aluminum Chloride
• Aluminum Compounds (administration & dosage, adverse effects)
• Antiperspirants (adverse effects, therapeutic use)
• Astringents (administration & dosage)
• Axilla
• Chlorides (administration & dosage, adverse effects)
• Dermatitis, Allergic Contact (diagnosis, etiology)
• Female
• Humans
• Hyperhidrosis (diagnosis, drug therapy)
• Male
• Treatment Outcome