Abstract | BACKGROUND: The performance of AlloDerm (LifeCell Corp., Branchburg, N.J.) in the setting of prosthetic breast reconstruction, infection, and radiation therapy has not been well documented. The purpose of this study was to review the author's experience with AlloDerm-assisted prosthetic breast surgery and determine the tolerance in the setting of infection and irradiation. METHODS: A total of 361 women and 476 breasts underwent reconstruction or revision with prosthetic devices. Of these, 76 women and 100 breasts underwent reconstruction using AlloDerm assistance. RESULTS: The incidence of postoperative infection was 5.85 percent (22 of 376) when prosthetic devices were used without AlloDerm and 5 percent (five of 100) when prosthetic devices were used with AlloDerm. Radiation therapy was a factor in 23 of 100 breasts reconstructed with AlloDerm. Adherence of AlloDerm was noted in 100 percent (23 of 23) and infection was noted in 8.7 percent (two of 23). The timing of irradiation (before or after AlloDerm insertion) did not affect the adherence or the infection rate. The overall incidence of seroma was 5 percent, the incidence of skin necrosis was 3 percent, and the incidence of incisional dehiscence was 4 percent. CONCLUSIONS:
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Authors | Maurice Y Nahabedian |
Journal | Plastic and reconstructive surgery
(Plast Reconstr Surg)
Vol. 124
Issue 6
Pg. 1743-1753
(Dec 2009)
ISSN: 1529-4242 [Electronic] United States |
PMID | 19952629
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Breast
(radiation effects)
- Breast Implantation
(adverse effects, methods)
- Breast Implants
(adverse effects)
- Breast Neoplasms
(pathology, radiotherapy, surgery)
- Cohort Studies
- Collagen
(therapeutic use)
- Esthetics
- Female
- Follow-Up Studies
- Graft Rejection
- Graft Survival
- Humans
- Incidence
- Mastectomy
(methods)
- Middle Aged
- Reoperation
- Retrospective Studies
- Risk Assessment
- Surgical Wound Infection
(diagnosis, epidemiology)
- Tissue Expansion Devices
(adverse effects)
- Treatment Outcome
- Wound Healing
(physiology)
- Young Adult
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