Eosinophilic fasciitis associated with L-tryptophan ingestion.

Abstract

A 62 year old woman taking L-tryptophan developed eosinophilic fasciitis shortly after starting an exercise class. She received prednisone without benefit but improved after azathioprine treatment was started and L-tryptophan was discontinued. As products containing L-tryptophan have recently been implicated in development of the eosinophilia-myalgia syndrome it is suggested that the use of L-tryptophan might have contributed to the development of eosinophilic fasciitis in this patient. Similarities with toxic oil syndrome are noted. Additional studies are warranted to determine the prevalence of L-tryptophan ingestion among patients diagnosed as having eosinophilic fasciitis.

• Authors: M E Hamilton
• Journal: Annals of the rheumatic diseases (Ann Rheum Dis) Vol. 50 Issue 1 Pg. 55-6 (Jan 1991) ISSN: 0003-4967 [Print] England
• PMID: 1994870 (Publication Type: Case Reports, Journal Article)

Chemical References

• Tryptophan

Topics

• Arm (pathology)
• Eosinophilia (chemically induced, pathology)
• Fasciitis (chemically induced, pathology)
• Female
• Humans
• Middle Aged
• Tryptophan (adverse effects)