[Advances in the researches of spermatogenic protein, Ropporin].

Ropporin has been identified as a spermatogenic cell-specific protein and may be involved in sperm maturation, motility, capacitation, hyperactivation and acrosome reaction. However, latest studies have shown that Ropporin is expressed weakly in normal non-testis tissues and highly in hematologic malignancies. Its highly conservative expression in mammalians demonstrates its importance to life. This paper updates the characterization, expression and its distribution, and biological function of Ropporin, and the advances in the clinical researches of the protein.
AuthorsJing Chen, Zhi-ming Cai, Yao-ting Gui
JournalZhonghua nan ke xue = National journal of andrology (Zhonghua Nan Ke Xue) Vol. 15 Issue 9 Pg. 833-5 (Sep 2009) ISSN: 1009-3591 [Print] China
PMID19947570 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't, Review)
Chemical References
  • Membrane Proteins
  • ROPN1 protein, human
  • rho GTP-Binding Proteins
  • Animals
  • Humans
  • Male
  • Membrane Proteins (physiology)
  • Spermatogenesis
  • rho GTP-Binding Proteins (physiology)

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