HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.

Abstract

HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.

• Authors: Surender Khurana, Philip J Norris, Michael P Busch, Barton F Haynes, Susan Park, Pretty Sasono, Koleka Mlisana, Abdool Karim Salim, Frederick M Hecht, Joseph Mulenga, Elwyn Chomba, Eric Hunter, Susan Allen, George Nemo, Isaac R Rodriguez-Chavez, Women's Interagency HIV Study Collaborative Study Group, Joseph B Margolick, Multicenter AIDS Cohort Study (MACS), Hana Golding
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 48 Issue 1 Pg. 281-5 (Jan 2010) ISSN: 1098-660X [Electronic] United States
• PMID: 19906903 (Publication Type: Comparative Study, Evaluation Study, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Antibodies, Viral

Topics

• Antibodies, Viral (blood)
• Female
• HIV Infections (diagnosis)
• HIV Seropositivity
• HIV-1 (immunology)
• Humans
• Immunoenzyme Techniques (methods)
• Male
• Sensitivity and Specificity