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Clinical benefits of the Boston Ocular Surface Prosthesis.

AbstractPURPOSE:
To evaluate the effects of the Boston Ocular Surface Prosthesis (Boston Foundation for Sight, Needham, Massachusetts, USA) on visual acuity (VA) and visual functioning in patients with severe corneal ectasia, irregular astigmatism, or ocular surface disease.
DESIGN:
Prospective, interventional case series.
METHODS:
The study examined the effects of this prosthesis on VA and visual functioning in consecutive patients with corneal ectasia, irregular astigmatism, or ocular surface disease who had failed conventional therapies and were seen at the Boston Foundation for Sight between January 1 and June 30, 2006. Outcomes were best-corrected VA using Snellen charts and visual functioning using the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) at 6 months. Clinical data were abstracted from medical records.
RESULTS:
Of the 101 patients, 80 were fitted with a prosthesis in one or both eyes, and follow-up Visual Functioning Questionnaire data were obtained in 69 eyes. Best-corrected VA improved by a change in mean logarithm of the minimal angle of resolution (logMAR) units of -0.39 (converted from Snellen) with a change of -0.54 logMAR units in patients with ectasia or astigmatism and -0.22 logMAR units in patients with ocular surface disease. Mean composite visual functioning scores increased from 57.0 to 77.8 (P < .0001). Improvements in composite Visual Functioning Questionnaire scores were similar in patients with ectasia or ocular surface disease; but vision-related subscores improved more in patients with ectasia, whereas subscores for ocular pain, role difficulties, and dependency improved more in patients with ocular surface disease.
CONCLUSIONS:
The Boston Ocular Surface Prosthesis significantly improved VA and visual functioning in patients with corneal ectasia, irregular astigmatism, and ocular surface disease who had failed conventional therapies.
AuthorsWilliam B Stason, Moaven Razavi, Deborah S Jacobs, Donald S Shepard, Jose A Suaya, Lynnette Johns, Perry Rosenthal
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 149 Issue 1 Pg. 54-61 (Jan 2010) ISSN: 1879-1891 [Electronic] United States
PMID19878920 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright 2010 Elsevier Inc. All rights reserved.
Topics
  • Adult
  • Astigmatism (physiopathology, rehabilitation)
  • Conjunctival Diseases (rehabilitation)
  • Contact Lenses
  • Corneal Diseases (physiopathology, rehabilitation)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Prostheses and Implants
  • Prosthesis Fitting
  • Sickness Impact Profile
  • Surveys and Questionnaires
  • Treatment Outcome
  • Vision Disorders (physiopathology, rehabilitation)
  • Visual Acuity (physiology)

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