Abstract | BACKGROUND: OBSERVATIONS: A review of patients with extensive alopecia areata was done. Six out of 10 patients responded to treatment with intralesional triamcinolone acetonide. In comparison to the non-responders, the responders tended to have exclamation mark hairs and a positive hair pull test at their initial physical examination, and exhibited improvement during the initial months of treatment. Complications were negligible, with mild reversible atrophy in three patients. The treatment was well tolerated and, in some patients, pain was minimized by use of a topical anesthetic agent applied under occlusion prior to the visit. CONCLUSION: Intralesional triamcinolone acetonide is a safe and effective treatment for patients with extensive alopecia areata. Patients with exclamation point hairs and a positive hair pull test may be more likely to respond.
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Authors | Kyung Hee Chang, Salinee Rojhirunsakool, Lynne J Goldberg |
Journal | Journal of drugs in dermatology : JDD
(J Drugs Dermatol)
Vol. 8
Issue 10
Pg. 909-12
(Oct 2009)
ISSN: 1545-9616 [Print] United States |
PMID | 19852119
(Publication Type: Journal Article)
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Chemical References |
- Anesthetics, Local
- Glucocorticoids
- Triamcinolone Acetonide
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Topics |
- Adolescent
- Adult
- Alopecia Areata
(drug therapy)
- Anesthetics, Local
(therapeutic use)
- Female
- Glucocorticoids
(administration & dosage, adverse effects, therapeutic use)
- Humans
- Injections, Intralesional
- Male
- Middle Aged
- Retrospective Studies
- Severity of Illness Index
- Treatment Outcome
- Triamcinolone Acetonide
(administration & dosage, adverse effects, therapeutic use)
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