Burow's solution-induced acute sensorineural hearing loss: report of two cases.

Abstract

This is the report of rare cases to show the potential ototoxicity of Burow's solution in clinical use. We encountered two cases of acute sensorineural hearing loss occurring after the administration of 8% Burow's solution (pH 2.93) into the tympanic cavities. Prior to treatment, both cases presented with tympanic membrane perforations in the posterior and inferior portions and a small amount of serous discharge. Fortunately, hearing loss recovered almost completely except for high tones within a few weeks. These two case reports demonstrate that the ototoxicity of Burow's solution should be considered when it is used to treat otitis media accompanied by tympanic membrane perforation.

• Authors: Naoki Oishi, Yasuhiro Inoue, Hideyuki Saito, Kaoru Ogawa
• Journal: Auris, nasus, larynx (Auris Nasus Larynx) Vol. 37 Issue 3 Pg. 369-72 (Jun 2010) ISSN: 1879-1476 [Electronic] Netherlands
• PMID: 19850426 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

Chemical References

• Acetates
• aluminum acetate

Topics

• Acetates (adverse effects)
• Audiometry, Pure-Tone
• Female
• Hearing Loss, Sensorineural (chemically induced, diagnosis, physiopathology)
• Humans
• Male
• Middle Aged
• Severity of Illness Index