Septo-optic dysplasia with bilateral congenital corneal anesthesia.

Abstract

Septo-optic dysplasia, or de Morsier syndrome, is characterized by optic nerve hypoplasia with an absent septum pellucidum and/or pituitary abnormalities. Congenital corneal anesthesia is a rare disorder that has been associated with many neurological disorders. Here we present a patient with both conditions who was successfully treated with permanent lateral tarsorrhaphy and aggressive lubrication. To our knowledge, congenital corneal anesthesia has not been reported in association with septo-optic dysplasia. The purpose of this report is to make pediatric ophthalmologists aware of a potential association since the diagnosis of congenital corneal anesthesia is often difficult and delayed.

• Authors: Clement C Chow, Rashmi Kapur, Michael G Wood, Pete Setabutr, Elmer Y Tu
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 13 Issue 5 Pg. 494-5 (Oct 2009) ISSN: 1528-3933 [Electronic] United States
• PMID: 19840731 (Publication Type: Case Reports, Journal Article)

Topics

• Corneal Diseases (complications, pathology)
• Humans
• Infant
• Magnetic Resonance Imaging
• Male
• Optic Nerve (abnormalities)
• Pain Insensitivity, Congenital (complications, pathology)
• Septo-Optic Dysplasia (complications, pathology)
• Septum Pellucidum (abnormalities)