Geometric analysis of melamine crystal: a problematic molecule inducing renal failure in melamine intoxication.

Abstract

In 2007, there was emerging toxic nephropathy due to melamine. Renal failure due to melamine crystal is noted in cases of melamine intoxication. In this article, the author studies the melamine crystal by the molecular docking technique and found that the size of crystal is a possible explanation for why the infantile population is more prone to develop renal failure after intoxication.

• Authors: Viroj Wiwanitkit
• Journal: Renal failure (Ren Fail) Vol. 31 Issue 5 Pg. 421-2 ( 2009) ISSN: 1525-6049 [Electronic] England
• PMID: 19839845 (Publication Type: Journal Article)

Chemical References

• Triazines
• melamine

Topics

• Acute Kidney Injury (chemically induced, physiopathology)
• Animals
• Biochemical Phenomena
• Crystallization
• Humans
• Poisoning (etiology, physiopathology)
• Structure-Activity Relationship
• Triazines (chemistry, toxicity)