Abstract |
A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo- radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA 19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo- radiotherapy and survived 20 months.
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Authors | Naohiko Kohya, Kazuyoshi Hashiguchi, Tomomi Yakabe, Atsushi Miyoshi, Takao Ohtsuka, Kenji Kitahara, Kohji Miyazaki |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 36
Issue 10
Pg. 1753-5
(Oct 2009)
ISSN: 0385-0684 [Print] Japan |
PMID | 19838042
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antimetabolites, Antineoplastic
- Biomarkers, Tumor
- Deoxycytidine
- Gemcitabine
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Topics |
- Aged
- Antimetabolites, Antineoplastic
(therapeutic use)
- Bile Duct Neoplasms
(diagnostic imaging, drug therapy, radiotherapy, surgery)
- Biomarkers, Tumor
(blood)
- Combined Modality Therapy
- Deoxycytidine
(analogs & derivatives, therapeutic use)
- Duodenal Neoplasms
(diagnostic imaging, drug therapy, secondary)
- Fatal Outcome
- Female
- Humans
- Lymphatic Metastasis
- Neoplasm Invasiveness
- Radiography
- Gemcitabine
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