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[Chemotherapy of skin and soft tissue tumors].

Abstract
Systemic chemotherapy may be used in locally advanced or metastatic soft tissue sarcoma for palliation. Malignant melanoma shows objective responses in about 20% of patients treated with chemotherapy or with cytokines (IL-2, alpha-IFN). Adjuvant chemotherapy has not proven to be effective in either of these entities. The risk of local recurrences in limbs however can be reduced by hyperthermic perfusion with cytotoxic agents. Neoadjuvant (preoperative) treatment of locally advanced tumors needs to be prospectively evaluated. Symptomatic Kaposi sarcoma can be effectively treated with alpha-IFN or chemotherapy.
AuthorsR Herrmann
JournalLangenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress (Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir) Pg. 919-21 ( 1990) ISSN: 0173-0541 [Print] Germany
Vernacular TitleChemotherapie von Haut- und Weichteiltumoren.
PMID1983679 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antineoplastic Agents
Topics
  • Antineoplastic Agents (therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Carcinoma, Squamous Cell (drug therapy, surgery)
  • Combined Modality Therapy
  • Humans
  • Lymphoma, T-Cell, Cutaneous (drug therapy, surgery)
  • Melanoma (drug therapy, surgery)
  • Prognosis
  • Sarcoma, Kaposi (drug therapy, surgery)
  • Skin Neoplasms (drug therapy, surgery)
  • Soft Tissue Neoplasms (drug therapy, surgery)

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