| Abstract | The study of the time course of changes in cell immunological parameters by a magnetic separation technique in human beings during the administration of plague vaccine in relation to the immunological load revealed the higher blood levels of all T lymphocyte subpopulations on day 14 after vaccination. These changes are most typical of a primary vaccinated cohort. The increased frequency of plague vaccine administration and multiple immunizations with live plague, anthrax, and tularemia vaccines produce the time-course of changes in T lymphocyte populations (subpopulations) in response to the regular administration of plague vaccine. A high immunological load in man also promotes a significant reduction in the level of B lymphocytes. |
| Authors | N V Bogacheva, I V Darmov, I V Borisevich, A V Kriuchkov, D V Pechenkin |
| Journal | Klinicheskaia laboratornaia diagnostika
(Klin Lab Diagn)
Issue 8
Pg. 24-7
(Aug 2009)
ISSN: 0869-2084 [Print] Russia (Federation) |
| PMID | 19827193
(Publication Type: English Abstract, Journal Article)
|
| Chemical References |
- Anthrax Vaccines
- Bacterial Vaccines
- Plague Vaccine
- Vaccines, Attenuated
|
| Topics |
- Anthrax Vaccines
(immunology)
- B-Lymphocytes
(immunology)
- Bacterial Vaccines
(immunology)
- Francisella tularensis
(immunology)
- Humans
- Immunity, Cellular
- Plague
(immunology, prevention & control)
- Plague Vaccine
(immunology)
- T-Lymphocyte Subsets
(immunology)
- T-Lymphocytes
(immunology)
- Vaccination
- Vaccines, Attenuated
(immunology)
|