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[The inhibition of the Sonic Hedgehog (SHh) pathway improves the effects of chemotherapy in a model of ductal carcinoma of the pancreas in mice].

AuthorsChristian-Jacques Larsen
JournalBulletin du cancer (Bull Cancer) Vol. 96 Issue 9 Pg. 829 (Sep 2009) ISSN: 1769-6917 [Electronic] France
Vernacular TitleL'inhibition de la voie Sonic Hedgehog (SHh) améliore les effets de la chimiothérapie dans un modèle d'adénocarcinome pancréatique canalaire chez la souris.
PMID19810163 (Publication Type: Journal Article)
Chemical References
  • Antimetabolites, Antineoplastic
  • Hedgehog Proteins
  • IPI-926
  • Neoplasm Proteins
  • Shh protein, mouse
  • Veratrum Alkaloids
  • Deoxycytidine
  • Gemcitabine
Topics
  • Animals
  • Antimetabolites, Antineoplastic (pharmacokinetics, therapeutic use)
  • Carcinoma, Pancreatic Ductal (drug therapy, metabolism)
  • Deoxycytidine (analogs & derivatives, pharmacokinetics, therapeutic use)
  • Hedgehog Proteins (antagonists & inhibitors)
  • Mice
  • Neoplasm Proteins (antagonists & inhibitors, metabolism)
  • Pancreatic Neoplasms (drug therapy, metabolism)
  • Veratrum Alkaloids (therapeutic use)
  • Gemcitabine

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