Abstract |
To report a successfully treated case of acquired night blindness associated with fundus white spots secondary to vitamin A deficiency. An ocular examination, electrophysiologic testing, as well as visual field and OCT examinations were obtained on a 61-year-old man with vitamin A deficiency who had previously undergone gastric bypass surgery. The patient had a re-evaluation after treatment with high doses of oral vitamin A. The patient was observed to have numerous white spots in the retina of each eye. Best-corrected visual acuity was initially 20/80 in each eye, which improved to 20/40-1 OU after oral vitamin A therapy for 2 months. Full field electroretinogram (ERG) testing, showed non-detectable rod function and a 34 and 41% reduction for 32-Hz flicker and single flash cone responses, respectively, below the lower limits of normal. Both rod and cone functions markedly improved after initiation of vitamin A therapy. Vitamin A deficiency needs to be considered in a patient with white spots of the retina in the presence of poor night vision.
|
Authors | Mohamed A Genead, Gerald A Fishman, Martin Lindeman |
Journal | Documenta ophthalmologica. Advances in ophthalmology
(Doc Ophthalmol)
Vol. 119
Issue 3
Pg. 229-33
(Dec 2009)
ISSN: 1573-2622 [Electronic] Netherlands |
PMID | 19809843
(Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Color
- Dark Adaptation
(drug effects)
- Electroretinography
- Fundus Oculi
- Gastric Bypass
- Humans
- Male
- Middle Aged
- Night Blindness
(drug therapy, etiology, pathology, physiopathology)
- Postoperative Complications
- Retina
(drug effects, pathology, physiopathology)
- Time Factors
- Treatment Outcome
- Visual Acuity
(drug effects)
- Vitamin A
(administration & dosage)
- Vitamin A Deficiency
(drug therapy, etiology, physiopathology)
- Vitamins
(administration & dosage)
|