Abstract | OBJECTIVE: To objectively assess the effect of Qiming Granule in the treatment of diabetic retinopathy (DR) by fluorescence fundus angiography (FFA). METHODS: In a multi-center, randomized, parallel controlled clinical trial, patients with DR were randomly assigned to the control group ( calcium dobesilate capsule) and the test group ( Qiming Granule). Changes in the retinal blood circulation time were recorded by FFA after 3 months of medication. RESULTS: Significant reduction was observed in the retinal arterio-venous circulation time (AVCT) in both groups (P<0.01), the value was 7.635+/-3.149 s before treatment and 5.165 +/-3.382 s after treatment in the treated group, and 7.737+/-3.413 s and 5.313+/-3.472 s in the control group respectively. Qiming Granule also reduced the arm-to- retinal circulation time (ARCT, P<0.05). The value was 17.867+/-3.872 s before treatment and 15.643+/-4.648 s after treatment in the treated group, and 17.217+/-3.833 s and 16.312+/-3.613 s in the control group (P>0.05) respectively. The ARCT in the tested group was reduced, with a statistically significant difference post-medication (P<0.01). CONCLUSION:
|
Authors | Xiang-xia Luo, Jun-guo Duan, Pin-zheng Liao, Lie Wu, Yang-gui Yu, Bo Qiu, Yu-liang Wang, Yu-min Li, Zheng-qin Yin, Xiao-ling Liu, Ke Yao |
Journal | Chinese journal of integrative medicine
(Chin J Integr Med)
Vol. 15
Issue 5
Pg. 384-8
(Oct 2009)
ISSN: 1672-0415 [Print] China |
PMID | 19802544
(Publication Type: Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Drugs, Chinese Herbal
- qiming
|
Topics |
- Aged
- Diabetes Mellitus, Type 2
(complications)
- Diabetic Retinopathy
(drug therapy, physiopathology)
- Drugs, Chinese Herbal
(adverse effects, pharmacology, therapeutic use)
- Female
- Fluorescein Angiography
- Humans
- Male
- Middle Aged
- Retinal Vessels
(drug effects, physiopathology)
|