Innate immune recognition in tuberculosis infection.

Abstract

In this review, an overview of the host's innate immune response against Mycobacterium tuberculosis will be provided. In particular, M. tuberculosis interaction with Toll-like receptors (TLRs), lung surfactant proteins and the antimicrobial mechanisms in the macrophage will be discussed along with their importance in shaping adaptive immunity to tuberculosis infection.

• Authors: Anthony G Tsolaki
• Journal: Advances in experimental medicine and biology (Adv Exp Med Biol) Vol. 653 Pg. 185-97 ( 2009) ISSN: 0065-2598 [Print] United States
• PMID: 19799120 (Publication Type: Journal Article, Review)

Chemical References

• Cytokines
• Lectins, C-Type
• Mannose Receptor
• Mannose-Binding Lectins
• Receptors, Cell Surface
• Receptors, Complement
• Receptors, Scavenger
• Toll-Like Receptors

Topics

• Animals
• Cytokines (immunology, metabolism)
• Dendritic Cells (immunology, metabolism, microbiology)
• Host-Pathogen Interactions (immunology)
• Humans
• Immunity, Innate
• Lectins, C-Type (immunology, metabolism)
• Mannose Receptor
• Mannose-Binding Lectins (immunology, metabolism)
• Mycobacterium tuberculosis (immunology)
• Phagocytosis (immunology)
• Phagosomes (immunology, microbiology)
• Receptors, Cell Surface (immunology, metabolism)
• Receptors, Complement (immunology, metabolism)
• Receptors, Scavenger (immunology, metabolism)
• Toll-Like Receptors (immunology, metabolism)
• Tuberculosis (immunology, metabolism)