The objective of this study was to evaluate the effect of
pregabalin in painful cervical or lumbosacral
radiculopathy treated in Primary Care settings under routine clinical practice. An observational, prospective 12-week secondary analysis was carried-out. Male and female above 18 years, naïve to
PGB, with refractory
chronic pain secondary to cervical/lumbosacral
radiculopathy were enrolled. SF-MPQ, Sheehan Disability Inventory, MOS Sleep Scale, Hospital Anxiety and Depression Scale and the EQ-5D were administered. A total of 490 (34%) patients were prescribed
PGB-monotherapy, 702 (48%) received
PGB add-on, and 159 (11%) were administered non-
PGB drugs. After 12 weeks, significant improvements in
pain, associated symptoms of anxiety, depression and sleep disturbances, general health; and level of disability were observed in the three groups, being significantly greater in
PGB groups. In routine medical practice, monotherapy or add-on
pregabalin is associated with substantial
pain alleviation and associated symptoms improvements in painful cervical or lumbosacral
radiculopathy.