Coexistence of Behcet's disease and chronic myelomonocyte leukemia with trisomy 8: a case report and review of the literature.

Abstract

Behçet's disease (BD) is a multisystem inflammatory vasculitis of unknown etiology and pathogenesis. Coexistence of BD along with hematological malignancies is extremely rare. We describe a patient diagnosed with BD and chronic myelomonocytic leukaemia (CMML) with trisomy 8. This case suggests that trisomy 8 may be involved in the concurrent manifestation of myelodysplastic syndrome (MDS) and BD with gastrointestinal ulcers.

• Authors: M G Mantzourani, K Chantziara, I Thanopoulou, H Variami, G Vaiopoulos, G A Pangalis
• Journal: Clinical and experimental rheumatology (Clin Exp Rheumatol) Vol. 27 Issue 2 Suppl 53 Pg. S85-7 ( 2009) ISSN: 0392-856X [Print] Italy
• PMID: 19796540 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Behcet Syndrome (complications)
• Chromosomes, Human, Pair 8
• Humans
• Karyotyping
• Leukemia, Myelomonocytic, Chronic (complications, genetics)
• Male
• Trisomy