| Abstract | OBJECTIVE: To analyze the prognostic factors for patients with acute-on-chronic liver failure, and to bulid a scoring system for assessment of the prognosis of liver failure. METHODS: 480 patients with acute-on-chronic liver failure in our hospital from January 2006 to June 2008 were enrolled in this study. The patients were divided into improved group and deteriorated group. The clinical data were analyzed by using chi square test, independent-Samples T Test and Binary logistic regression. RESULTS: The factors that significantly affected the prognosis of Acute-on-chronic Liver Failure included age, hepatitis or liver cirrhosis, Staging, Hyponatremias, alpha-fetoprotein (AFP), the prothrombin time activity (PTA), total bilirubin (TBil), creatinine (Cr), albumin (ALB) and Hepatic encephalopathy, ascites, alimentary tract hemorrhage (P less than 0.05, P less than 0.01). PTA, Hyponatremias, hepatitis or liver cirrhosis, Hepatic encephalopathy and alimentary tract hemorrhage were independent risk factors of prognosis. CONCLUSION: PTA, Hyponatremias, hepatitis or liver cirrhosis, Hepatic encephalopathy and alimentary tract hemorrhage are inportant to build a scoring system to assess the prognosis of Acute-on-chronic Liver Failure and may be useful to guide clinical treatment. DOI: 10.3760/cma.j.issn.1007-3418.2009.09.011. |
| Authors | Cai-Yan Zhao, Lei Yan, Ya-Dong Wang, Wei Wang, Jun-Ying Zhou, Zhen Zhen
(Affiliation: Department of Infectious Disease, Third Affiliated Hospital, Hebei Medical University, Shijiazhuang 050051, China.)
|
| Journal | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
(Zhonghua Gan Zang Bing Za Zhi)
Vol. 17
Issue 9
Pg. 683-7
(Sep 2009)
ISSN: 1007-3418 [Print] China |
| PMID | 19785957
(Publication Type: English Abstract, Journal Article)
|
