Gigantomastia and autoimmunity: a case report.

Abstract

Gigantomastia is a rare breast condition characterised by diffuse, rapid, and excessive breast hypertrophy that can result in symptoms ranging from pain to necrosis and sepsis. It typically occurs in the setting of marked hormonal changes such as puberty and pregnancy. Rarely, gigantomastia has been reported to develop in the setting of an autoimmune illness. We present a case of gigantomastia developing in a patient with systemic lupus erythematosus, who was treated with methotrexate and bilateral mammoplasty.

• Authors: E N Le, L Y McGirt, R Abuav
• Journal: Lupus (Lupus) Vol. 18 Issue 11 Pg. 1015-8 (Oct 2009) ISSN: 1477-0962 [Electronic] England
• PMID: 19762405 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antirheumatic Agents
• Methotrexate

Topics

• Adult
• Antirheumatic Agents (therapeutic use)
• Autoimmunity (immunology)
• Breast (pathology, surgery)
• Female
• Humans
• Hypertrophy (etiology, pathology, therapy)
• Lupus Erythematosus, Systemic (complications, pathology)
• Mammaplasty
• Methotrexate (therapeutic use)
• Pregnancy