[Pedigree analysis and prosthodontic treatment of patients with dentinogenesis imperfecta type II].

Abstract

PURPOSE:

To study the heritable character and explore the prosthodontic treatment of opalescent dentin, also known as dentinogenesis imperfecta type II(DGI-II).

METHODS:

Pedigree analysis was performed in the family members of patients with DGI-II found in Shanghai. The proband was treated with ceramometal restorations and investigated the treatment status of the DGI-II affected individuals in the family.

RESULTS:

Five sequential generations with DGI-II were found in this family. The prevalence of later generation was approximately 50%. The rate of prosthodontic treatment was 90% nearly, including ceramometal restorations in the most of the patients and removable partial dentures in the others. The esthetic and mastication functions of the patients were good after treatment.

CONCLUSIONS:

DGI-II showed a autosomal dominant pattern of inheritance. Ceramaometal restorations can prevent the affected teeth from abrasive and fracture, and also can help rehabilitate the esthetic and mastication functions of the teeth.

• Authors: Hong Gan, Xiu-yin Zhang, Xiao-cen Xu
• Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology (Shanghai Kou Qiang Yi Xue) Vol. 18 Issue 4 Pg. 337-41 (Aug 2009) ISSN: 1006-7248 [Print] China
• PMID: 19760002 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Extracellular Matrix Proteins
• Phosphoproteins

Topics

• China
• Dentinogenesis Imperfecta
• Extracellular Matrix Proteins
• Humans
• Pedigree
• Phosphoproteins
• Prosthodontics