Chemical avulsion with urea nail lacquer.

Abstract

BACKGROUND:

Among the therapeutic possibilities for onychomycosis, chemicalnail avulsion is a logical approach to the eradication of the pathogen.

METHODS:

A new formulation was used as a nail lacquer containing 40% urea in a film-forming solution in 10 patients presenting with onychomycosis. The urea nail lacquer was applied with a brush twice a day for 1 week by the patient and for a further week in two patients presenting total dystrophic onychomycosis.

RESULTS:

This transungual delivery system weakens the nail plate/nail bed attachment in the diseased area.

CONCLUSION:

The urea nail lacquer is comfortable for the patient and allows easy removal of the affected part of the fungal nail plate.

• Authors: R Baran, A Tosti
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 13 Issue 4 Pg. 161-4 (Dec 2002) ISSN: 0954-6634 [Print] England
• PMID: 19753735 (Publication Type: Journal Article)

Chemical References

• Antifungal Agents
• Imidazoles
• Urea
• bifonazole

Topics

• Administration, Cutaneous
• Adult
• Aged
• Antifungal Agents (administration & dosage)
• Cohort Studies
• Female
• Foot Dermatoses (drug therapy, microbiology, pathology)
• Humans
• Imidazoles (administration & dosage)
• Lacquer
• Male
• Middle Aged
• Onychomycosis (drug therapy, microbiology, pathology)
• Urea (administration & dosage)
• Young Adult