HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Inappropriate cardioverter-defibrillator discharge continues to be a major problem in clinical practice.

AbstractBACKGROUND:
The purpose of this study was to determine the rate and causes of inappropriate rhythm detection, and to compare adequacy of ventricular arrhythmia detection by single-chamber and dual-chamber cardioverter-defibrillators (ICD).
METHODS:
We evaluated 190 patients (age 57.2 +/- 11.2 years) with ICD.
FOLLOW-UP:
34.3 +/- +/- 22 months. Dual-chamber ICD was used in 54 patients.
RESULTS:
We evaluated 2244 arrhythmia events recognized as of ventricular origin, including ventricular tachycardia and ventricular fibrillation. 431 events (19.2%) were recognized erroneously and resulted in an inappropriate ICD discharge. Most cases of inappropriate therapies (182 events, 42.23%) were due to atrial fibrillation or flutter. Overall, inappropriate arrhythmia detection was found in 64 (33.6%) of 190 patients. In terms of the number of affected patients, the most common cause of inappropriate ICD discharge was sinus tachycardia - 23 (12.1%) patients, followed by atrial fibrillation - 16 (8.4%) patients. Among 54 patients with dual-chamber ICD, inappropriate therapy was noted in 21 (38.8%) patients, (T wave oversensing, sinus tachycardia and atrial fibrillation etc.). No significant difference was seen in the rate of inappropriate therapy due to a rapid supraventricular rhythm between patients with single-chamber versus dual-chamber ICD. In contrast, patients with single-chamber ICD more often experienced inappropriate therapy due to atrial fibrillation (155 vs. 28 patients) and sinus tachycardia (66 vs. 9 patients).
CONCLUSIONS:
Despite of introduction of new generations of ICDs, the problem of inappropriate ICD discharge could not be eliminated. The major problem is distinction between supraventricular arrhythmia and ventricular tachyarrhythmia.
AuthorsŁukasz Jodko, Zdzisława Kornacewicz-Jach, Jarosław Kaźmierczak, Ryszard Rzeuski, Joanna Zielonka, Robert Kaliszczak, Krzysztof Safranow
JournalCardiology journal (Cardiol J) Vol. 16 Issue 5 Pg. 432-9 ( 2009) ISSN: 1898-018X [Electronic] Poland
PMID19753522 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Atrial Fibrillation (diagnosis, physiopathology)
  • Defibrillators, Implantable
  • Diagnosis, Differential
  • Diagnostic Errors
  • Electric Countershock (adverse effects, instrumentation)
  • Equipment Design
  • Equipment Failure
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Signal Processing, Computer-Assisted
  • Tachycardia, Sinus (diagnosis, physiopathology)
  • Tachycardia, Ventricular (diagnosis, physiopathology, therapy)
  • Time Factors
  • Treatment Outcome
  • Ventricular Fibrillation (diagnosis, physiopathology, therapy)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: