The leading role of allergic components was established in some rare patterns of
prostatitis. To develop the methods applicable for differential diagnosis of allergic
prostatitis, the authors followed up 60 patients aged from 15 to 53 years who suffered from chronic
prostatitis and 10 normal controls. The patients with
bacterial disease, abacterial
prostatitis with concurrent allergic components or subjects with allergic
prostatitis were enrolled in the study. Immunoassay was an essential part in the diagnosis of allergic
prostatitis. The study revealed a dramatic inhibition of ejaculate gamma-
glutamine transferase in those who suffered from an abacterial pattern with allergic component and almost three-fold in those with allergic
prostatitis. Certain though insignificant decrease in the ejaculate gamma-
glutamine transferase was documented in patients with bacterial
prostatitis. Investigations of ejaculate
IgE revealed quite an opposite picture: 10-fold increase in
IgE levels in the ejaculate of patients with allergic
prostatitis as compared with other groups, controls in their number. Besides, patients with allergic
prostatitis had three-fold higher
IgE in the ejaculate than in the blood serum. The aforementioned phenomenon failed to be observed in patients with other patterns of
prostatitis. Decreased ejaculate gamma-
glutamine transferase and increased
IgE can be regarded as criteria for differential diagnosis of allergic
prostatitis.