Abstract | OBJECTIVE: STUDY DESIGN: This was a multicenter pilot case series to evaluate cryoablation of uterine fibroids using laparoscopically assisted placement of 17-gauge cryoablation needles. Patient satisfaction was documented with a validated Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire. Procedural efficacy was evaluated by assessing fibroid shrinkage. Treatment was followed by assessments at 3, 6, and 12 months. RESULTS: Median fibroid volume reduction was 43.3% (19 patients) and 66.4% (15 patients) at 6 and 12 months, respectively. Median UFS-QOL score improvement was 61.9% and 66.7% at 6 and 12 months, respectively. Additionally, patients experienced marked improvement of bleeding and fibroid bulk symptoms. The median Symptom Severity Score at baseline was 50, 25.0 (-59%) at 6 months, and 12.5 (-66.7%) at 12 months. CONCLUSION:
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Authors | Moty Pansky, Bryan D Cowan, Maya Frank, Harriette L Hampton, Stephen Zimberg |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 201
Issue 6
Pg. 571.e1-7
(Dec 2009)
ISSN: 1097-6868 [Electronic] United States |
PMID | 19716538
(Publication Type: Clinical Trial, Journal Article, Multicenter Study)
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Topics |
- Adult
- Cryosurgery
(instrumentation)
- Female
- Humans
- Laparoscopy
- Leiomyoma
(surgery)
- Middle Aged
- Needles
- Pilot Projects
- Prospective Studies
- Treatment Outcome
- Uterine Neoplasms
(surgery)
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