HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Ceftazidime monotherapy is as effective as ceftazidime combined with gentamicin in the treatment of febrile neutropenic patients.

Abstract
To evaluate the efficacy of ceftazidime monotherapy in the empirical treatment of febrile neutropenic patients, a randomized trial was performed of ceftazidime (C) vs. ceftazidime and gentamicin (C + G) with the addition of teicoplanin (T) for those patients with a long intravenous line-associated infection. Success without modification at the end of treatment was seen in 32.7% (C), 28.3% (C + G), 52.4% (C + T) and 65.2% (C + G + T). Monotherapy with ceftazidime is as effective as when used in combination with an aminoglycoside in neutropenia.
AuthorsS E Kinsey, S J Machin, A H Goldstone
JournalThe Journal of hospital infection (J Hosp Infect) Vol. 15 Suppl A Pg. 49-53 (Apr 1990) ISSN: 0195-6701 [Print] England
PMID1971645 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Anti-Bacterial Agents
  • Gentamicins
  • Glycopeptides
  • Teicoplanin
  • Ceftazidime
Topics
  • Agranulocytosis (complications)
  • Anti-Bacterial Agents (therapeutic use)
  • Cause of Death
  • Ceftazidime (therapeutic use)
  • Drug Therapy, Combination
  • Female
  • Fever (drug therapy, etiology, mortality)
  • Gentamicins (therapeutic use)
  • Glycopeptides (therapeutic use)
  • Humans
  • Male
  • Neutropenia (complications)
  • Randomized Controlled Trials as Topic
  • Teicoplanin

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: