Cerebral aspergillosis caused by Aspergillus granulosus.

Abstract

Disseminated disease by Aspergillus granulosus has been reported only once previously in a cardiac transplant recipient. We report a fatal central nervous system infection in a lung transplant recipient. Key features of this species in the section Usti include growth at 37 degrees C and large, randomly spaced aggregates of variably shaped Hülle cells.

• Authors: Deanna A Sutton, Brian L Wickes, Anna M Romanelli, Michael G Rinaldi, Elizabeth H Thompson, Annette W Fothergill, Megan K Dishop, Okan Elidemir, George B Mallory, Siby P Moonnamakal, Adekunle M Adesina, Marc G Schecter
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 47 Issue 10 Pg. 3386-90 (Oct 2009) ISSN: 1098-660X [Electronic] United States
• PMID: 19710280 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)

Chemical References

• Antifungal Agents
• DNA, Fungal
• DNA, Ribosomal
• DNA, Ribosomal Spacer
• RNA, Fungal
• RNA, Ribosomal, 28S

Topics

• Adolescent
• Antifungal Agents (pharmacology)
• Aspergillus (cytology, genetics, isolation & purification)
• Cerebrum (microbiology, pathology)
• DNA, Fungal (chemistry, genetics)
• DNA, Ribosomal (chemistry, genetics)
• DNA, Ribosomal Spacer (chemistry, genetics)
• Fatal Outcome
• Genes, rRNA
• Humans
• Immunocompromised Host
• Lung Transplantation (adverse effects)
• Male
• Microbial Sensitivity Tests
• Microscopy
• Molecular Sequence Data
• Neuroaspergillosis (diagnosis, microbiology)
• RNA, Fungal (genetics)
• RNA, Ribosomal, 28S (genetics)
• Sequence Analysis, DNA