Abstract | BACKGROUND: Children undergoing hypospadias repair need to be protected from highly unpleasant sensory and emotional experiences during and after surgery. We designed a double-blinded, randomized, and placebo-controlled study to compare the efficacy of a low-dose (2 microg x kg(-1)) of intrathecal morphine with placebo for postoperative pain control of children undergoing repair of hypospadias surgery with spinal anesthesia. METHODS: RESULTS: Forty-nine patients completed the trial. Fifteen patients (60%) in group P received supplementary analgesics within the first 12 h compared to only four patients (16.7%) in group M (P = 0.005). Mean duration of analgesia was 480 +/- 209 and 720 +/- 190 min in group P and group M respectively (P = 0.009). The groups were similar in postoperative side effects. CONCLUSION:
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Authors | Seza Apiliogullari, Ates Duman, Funda Gok, Isak Akillioglu, Ilhan Ciftci |
Journal | Paediatric anaesthesia
(Paediatr Anaesth)
Vol. 19
Issue 11
Pg. 1078-83
(Nov 2009)
ISSN: 1460-9592 [Electronic] France |
PMID | 19708911
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics
- Analgesics, Opioid
- Anesthetics, Local
- Morphine
- Bupivacaine
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Topics |
- Analgesics
(administration & dosage)
- Analgesics, Opioid
(administration & dosage)
- Anesthesia, Spinal
(methods)
- Anesthetics, Local
(administration & dosage)
- Bupivacaine
(administration & dosage)
- Child
- Child, Preschool
- Dose-Response Relationship, Drug
- Double-Blind Method
- Humans
- Hypospadias
(surgery)
- Male
- Morphine
(administration & dosage)
- Pain, Postoperative
(prevention & control)
- Treatment Outcome
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