Abstract | BACKGROUND AND AIM OF THE WORK: METHODS: We considered 163 paediatric patients with suspected infectious mononucleosis and we tested their serums to detect heterophil antibodies (using an inexpensive and rapid test) and specific immunoglobulins directed against Epstein-Barr virus (EBV) (these assays are known to be characterized by high sensitivity and specificity, but are more expensive and time-consuming). RESULTS: By comparing the results of the rapid test with those of the other assays, we found that the sensitivity of the first test was 61.8%, whereas its specificity was sufficiently high (about 90%). CONCLUSIONS:
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Authors | Giorgio Tamaro, Michela Donato, Tanja Princi, Sergio Parco |
Journal | Acta bio-medica : Atenei Parmensis
(Acta Biomed)
Vol. 80
Issue 1
Pg. 47-50
(Apr 2009)
ISSN: 0392-4203 [Print] Italy |
PMID | 19705620
(Publication Type: Controlled Clinical Trial, Journal Article)
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Chemical References |
- Antibodies, Heterophile
- Antibodies, Viral
- Capsid Proteins
- Immunoglobulin G
- Immunoglobulin M
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Topics |
- Agglutination
- Antibodies, Heterophile
(blood)
- Antibodies, Viral
(blood)
- Capsid Proteins
(blood)
- Child
- Female
- Herpesvirus 4, Human
(immunology)
- Humans
- Immunoenzyme Techniques
- Immunoglobulin G
(blood)
- Immunoglobulin M
(blood)
- Infectious Mononucleosis
(blood, diagnosis, immunology)
- Male
- Reproducibility of Results
- Sensitivity and Specificity
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