[The development of recent strategies in the treatment of urticaria as a result of clinically oriented research].

Abstract

New therapeutic approaches in urticaria are presented with special respect to chronic and physical types including symptomatic dermographism, cholinergic urticaria, pressure and solar urticaria as well as vibratory angioedema. Clinical efficacies of several antihistamines (clemastine, astemizole, terfenadine, acrivastine, hydroxyzine, cimetidine), of ketotifen as a H1 receptor antagonist and mast cell stabilizer, of tricyclic antidepressant doxepin with H1 and H2 antagonist properties, of the calcium channel antagonist nifedipine, of topical corticosteroids and of the attenuated androgen danazol are presented. The data are specified by a detailed description of the design and particular conditions of the underlying study protocols.

• Authors: F Lawlor, M W Greaves
• Journal: Zeitschrift fur Hautkrankheiten (Z Hautkr) Vol. 65 Issue 1 Pg. 17-27 (Jan 1990) ISSN: 0301-0481 [Print] Germany
• Vernacular Title: Die Entwicklung neuer Strategien der Urticariatherapie als ein Ergebnis klinisch orientierter Forschung.
• PMID: 1970207 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Histamine H1 Antagonists

Topics

• Angioedema (drug therapy)
• Histamine H1 Antagonists (therapeutic use)
• Humans
• Urticaria (drug therapy, etiology)