Abstract | BACKGROUND AND AIMS: Oxidative stress has been involved in the early steps of atherosclerosis and previous studies on hypercholesterolemic hamsters have shown that non-enzymatic antioxidant could prevent fatty streak formation. Therefore, we investigated whether a melon juice extract ( Extramel((R))) rich in superoxide dismutase (SOD) would prevent the development of early atherosclerosis. METHODS AND RESULTS: CONCLUSION: These findings support the view that chronic consumption of melon juice extract rich in SOD has potential beneficial effects with respect to the development of atherosclerosis and liver steatosis, emphasizing its use as potential dietary therapy.
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Authors | K Décordé, E Ventura, D Lacan, J Ramos, J-P Cristol, J-M Rouanet |
Journal | Nutrition, metabolism, and cardiovascular diseases : NMCD
(Nutr Metab Cardiovasc Dis)
Vol. 20
Issue 5
Pg. 301-7
(Jun 2010)
ISSN: 1590-3729 [Electronic] Netherlands |
PMID | 19695852
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Dietary Fats
- Lipids
- Plant Extracts
- Superoxides
- Superoxide Dismutase
- Extramel
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Topics |
- Animals
- Aorta
(metabolism)
- Atherosclerosis
(drug therapy)
- Cricetinae
- Dietary Fats
(administration & dosage)
- Fatty Liver
(prevention & control)
- Lipids
(blood)
- Male
- Mesocricetus
- Plant Extracts
(therapeutic use)
- Superoxide Dismutase
(metabolism, therapeutic use)
- Superoxides
(metabolism)
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