Abstract | BACKGROUND: AIM: METHODS: Fluorescent microscopy and real-time polymerase chain reaction were used to detect different types of cell death and gene expression, respectively, in neonatal rat cardiomyocyte cultures exposed to anoxia-reoxygenation. RESULTS: CONCLUSION: Although PIs are injurious, they may be cardioprotective in low doses; ie, they do not result in cell death. Moreover, PIs initiate the protective mechanisms that prevent cell damage by changing the expression of several genes.
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Authors | Olga V Surova, Vasyl S Nagibin, Lesya V Tumanovskaya, Victor E Dosenko, Alexey A Moibenko |
Journal | Experimental and clinical cardiology
(Exp Clin Cardiol)
Vol. 14
Issue 2
Pg. e57-61
( 2009)
ISSN: 1205-6626 [Print] Canada |
PMID | 19675822
(Publication Type: Journal Article)
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