Abstract |
Six 1-glyceryl ethers (1-6) were isolated from the red alga-sponge assemblage Ceratodictyon spongiosum/Haliclona cymaeformis. Structural assignments were conducted by interpretation of spectroscopic data and the modified Mosher's method. Four allylic alcohols were obtained as a pair of epimeric mixtures (3/4 and 5/6). These glyceryl ethers exhibited weak cytotoxic activity against HeLa human cervical cancer cells.
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Authors | Takuya Akiyama, Reiko Ueoka, Rob W M van Soest, Shigeki Matsunaga |
Journal | Journal of natural products
(J Nat Prod)
Vol. 72
Issue 8
Pg. 1552-4
(Aug 2009)
ISSN: 1520-6025 [Electronic] United States |
PMID | 19670881
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Glyceryl Ethers
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Topics |
- Animals
- Antineoplastic Agents
(chemistry, isolation & purification, pharmacology)
- Drug Screening Assays, Antitumor
- Glyceryl Ethers
(chemistry, isolation & purification, pharmacology)
- Haliclona
(chemistry)
- HeLa Cells
- Humans
- Molecular Structure
- Rhodophyta
(chemistry)
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