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Ceratodictyols, 1-glyceryl ethers from the red alga-sponge association Ceratodictyon spongiosum/Haliclona cymaeformis.

Abstract
Six 1-glyceryl ethers (1-6) were isolated from the red alga-sponge assemblage Ceratodictyon spongiosum/Haliclona cymaeformis. Structural assignments were conducted by interpretation of spectroscopic data and the modified Mosher's method. Four allylic alcohols were obtained as a pair of epimeric mixtures (3/4 and 5/6). These glyceryl ethers exhibited weak cytotoxic activity against HeLa human cervical cancer cells.
AuthorsTakuya Akiyama, Reiko Ueoka, Rob W M van Soest, Shigeki Matsunaga
JournalJournal of natural products (J Nat Prod) Vol. 72 Issue 8 Pg. 1552-4 (Aug 2009) ISSN: 1520-6025 [Electronic] United States
PMID19670881 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents
  • Glyceryl Ethers
Topics
  • Animals
  • Antineoplastic Agents (chemistry, isolation & purification, pharmacology)
  • Drug Screening Assays, Antitumor
  • Glyceryl Ethers (chemistry, isolation & purification, pharmacology)
  • Haliclona (chemistry)
  • HeLa Cells
  • Humans
  • Molecular Structure
  • Rhodophyta (chemistry)

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