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Polyethylene glycol-modified adenosine deaminase improved lung disease but not liver disease in partial adenosine deaminase deficiency.

AuthorsRaz Somech, Yew Hon Lai, Eyal Grunebaum, Nicole Le Saux, Ernest Cutz, Chaim M Roifman
JournalThe Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 124 Issue 4 Pg. 848-50 (Oct 2009) ISSN: 1097-6825 [Electronic] United States
PMID19665771 (Publication Type: Case Reports, Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Immunoglobulins
  • Adenosine Deaminase
  • pegademase bovine
Topics
  • Adenosine Deaminase (deficiency, therapeutic use)
  • Erythrocytes (enzymology, metabolism)
  • Follow-Up Studies
  • Humans
  • Immunoglobulins (blood)
  • Infant, Newborn
  • Liver Diseases (complications, drug therapy, enzymology)
  • Lung Diseases (complications, drug therapy, enzymology)
  • Lymphocytes (enzymology, metabolism)
  • Male
  • Severe Combined Immunodeficiency (complications, drug therapy, enzymology)

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