Trophoblastic tumour, oral contraceptive therapy and pregnancy associated alpha2-glycoprotein (PAAG), case report.

Abstract

Pregnancy associated alpha2-glycoprotein (PAAG) and human chorionic gonadotrophin (HCG) levels were studied in a patient with an invasive mole who was being treated with cytotoxic drugs and oral contraceptives. Both the PAAG and HCG levels fell during cytotoxic drug treatment while oral contraceptives caused a rise in PAAG concentrations. A relation between oestrogen-induced PAAG and prolonged survival of trophoblastic tumour is proposed.

• Authors: B Teisner, B Mogensen, J Folkersen, S E Svehag
• Journal: British journal of obstetrics and gynaecology (Br J Obstet Gynaecol) Vol. 84 Issue 8 Pg. 630-2 (Aug 1977) ISSN: 0306-5456 [Print] England
• PMID: 196614 (Publication Type: Case Reports, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Contraceptives, Oral
• Glycoproteins
• Methotrexate

Topics

• Adult
• Chorionic Gonadotropin (urine)
• Contraceptives, Oral (therapeutic use)
• Female
• Glycoproteins (blood)
• Humans
• Methotrexate (therapeutic use)
• Pregnancy
• Trophoblastic Neoplasms (blood, drug therapy)
• Uterine Neoplasms (blood)