Efficacy of albaconazole against Candida albicans in a vaginitis model.

Abstract	The efficacy of albaconazole (ABC) was evaluated using a murine model of vaginal Candida albicans infection. Both ABC and fluconazole (FLC) were effective in reducing the fungal load from vaginas of infected mice; however, ABC demonstrated encouraging activities against an FLC-resistant strain, with trends toward superiority over FLC in some treatment groups.
Authors	Gloria M González, Efrén Robledo, Elvira Garza-González, Mariana Elizondo, J Gerardo González
Journal	Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 53 Issue 10 Pg. 4540-1 (Oct 2009) ISSN: 1098-6596 [Electronic] United States
PMID	19635949 (Publication Type: Journal Article)
Chemical References	Antifungal Agents Quinazolines Triazoles Fluconazole albaconazole
Topics	Administration, Oral Animals Antifungal Agents (pharmacology, therapeutic use) Candida albicans (drug effects) Female Fluconazole (pharmacology, therapeutic use) Mice Mice, Inbred BALB C Quinazolines (pharmacology, therapeutic use) Triazoles (pharmacology, therapeutic use) Vaginitis (drug therapy, microbiology)

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