Group A streptococcal necrotizing fasciitis of the eyelids and face managed with debridement and adjunctive intravenous immunoglobulin.

Abstract

The authors describe a patient with right upper and lower eyelid necrosis combined with facial, neck, and chest edema and sepsis secondary to Group A streptococcal infection after minor trauma. This is an uncommon, life-threatening condition that was successfully treated with limited surgical debridement, antimicrobial therapy, and intravenous immunoglobulin. Oculoplastic surgeons should be aware of the indications and potential benefit of adjunctive intravenous immunoglobulin therapy for Group A Streptococcus-induced necrotizing fasciitis.

• Authors: Vinay K Aakalu, Kiran Sajja, James L Cook, Amjad Z Ahmad
• Journal: Ophthalmic plastic and reconstructive surgery (Ophthalmic Plast Reconstr Surg) 2009 Jul-Aug Vol. 25 Issue 4 Pg. 332-4 ISSN: 1537-2677 [Electronic] United States
• PMID: 19617804 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Immunoglobulins, Intravenous
• Immunologic Factors

Topics

• Adult
• Debridement (methods)
• Diagnosis, Differential
• Eye Infections, Bacterial (diagnosis, microbiology, therapy)
• Eyelid Diseases (diagnosis, microbiology, therapy)
• Eyelids (microbiology)
• Face (microbiology)
• Facial Dermatoses (diagnosis, microbiology, therapy)
• Fasciitis, Necrotizing (diagnosis, microbiology, therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Immunologic Factors (administration & dosage)
• Male
• Streptococcal Infections (diagnosis, microbiology, therapy)
• Streptococcus pyogenes (isolation & purification)