Effects of oral antibiotic roxithromycin on quality of life in acne patients.

Abstract

Macrolides are effective for inflammatory acne, but there are not many studies on roxithromycin. In this study, patients with acne were surveyed for improvement of their quality of life after treatment with roxithromycin. Patients were orally given roxithromycin 300 mg daily for 2-4 weeks. At the time of pre- and post-treatment, the dermatologists graded the severity of acne symptoms, and the patients answered questionnaires. In 123 half faces of 76 patients, 80 half faces were improved, 42 half faces were not changed, and one half face was deteriorated. The score of "symptom and feeling" and "leisure" in DLQI-J and "emotions" and "symptoms" in Skindex-29-J were significantly decreased after roxithromycin treatment. Roxithromycin has a therapeutic effect on inflammatory acne and leads to improvement of quality of life in the patients.

• Authors: Miwa Kobayashi, Kenji Kabashima, Motonobu Nakamura, Yoshiki Tokura
• Journal: The Journal of dermatology (J Dermatol) Vol. 36 Issue 7 Pg. 383-91 (Jul 2009) ISSN: 1346-8138 [Electronic] England
• PMID: 19583686 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Roxithromycin

Topics

• Acne Vulgaris (drug therapy, pathology, psychology)
• Administration, Oral
• Adolescent
• Adult
• Anti-Bacterial Agents (administration & dosage, therapeutic use)
• Asian People
• Female
• Humans
• Male
• Quality of Life
• Roxithromycin (administration & dosage, therapeutic use)
• Surveys and Questionnaires
• Young Adult