Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA).

Abstract	Antimicrobial properties of plants essential oils (EOs) have been investigated through several observations and clinical studies which purpose them as potential tools to overcome the microbial drug resistance problem. The aim of this research is to study the antibacterial effect of two traditional plants essential oils, Thymus vulgaris and Eucalyptus globulus against clinical isolates of Methicillin resistant Staphylococcus aureus (MRSA) and other standard bacterial strains through disk diffusion and agar dilution methods. Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) analysis examined the chemical composition of the oils. Results revealed both of oils to possess degrees of antibacterial activity against Gram (+) and Gram (-) bacteria. T. vulgaris EO showed better inhibitory effects than E. globulus essential oil. GC analysis of T. vulgaris resulted in thymol as the oil major compound whereas GC/MS assay exhibited eucalyptol as the most abundant constitute of E. globulus EO. These results support previous studies on these oils and suggest an additional option to treat MRSA infections. Clinical and further analytical trials of these data are necessary to confirm the obtained outcomes.
Authors	A Tohidpour, M Sattari, R Omidbaigi, A Yadegar, J Nazemi
Journal	Phytomedicine : international journal of phytotherapy and phytopharmacology (Phytomedicine) Vol. 17 Issue 2 Pg. 142-5 (Feb 2010) ISSN: 1618-095X [Electronic] Germany
PMID	19576738 (Publication Type: Journal Article)
Copyright	Copyright 2009. Published by Elsevier GmbH.
Chemical References	Anti-Bacterial Agents Oils, Volatile Plant Extracts
Topics	Anti-Bacterial Agents (isolation & purification, pharmacology) Eucalyptus (chemistry) Methicillin-Resistant Staphylococcus aureus (drug effects) Microbial Sensitivity Tests Oils, Volatile (isolation & purification, pharmacology) Plant Components, Aerial Plant Extracts (isolation & purification, pharmacology) Thymus Plant (chemistry)

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