[Chemical studies of Salvia miltiorrhiza f. alba].

Abstract

Fourteen constituents were isolated from the roots of Salvia miltiorrhiza f. alba. Two of them were new compounds and were named 1,2,15,16-tetrahydrotanshiquinone (I) and tanshinaldehyde (II). The others were identified as Ro-090680 (III), dihydroisotanshone I (IV), danshexinkun B (V), miltirone (VI), nortanshinone (VII), hydroxytanshinone II-A (VIII), tanshinone I (IX), dihydrotanshinone I (X), tanshinone II-A (XI), cryptotanshinone (XII), methylenetanshiquinone (XIII), methyltanshinonate (XIV), I and III showed inhibitory activity against P388 Leukemia cell in vitro. III was reported to be a potent inhibitor of rabbit platelet aggregation induced by collagen.

• Authors: Z T Li, B J Yang, G E Ma
• Journal: Yao xue xue bao = Acta pharmaceutica Sinica (Yao Xue Xue Bao) Vol. 26 Issue 3 Pg. 209-13 ( 1991) ISSN: 0513-4870 [Print] China
• PMID: 1957662 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drugs, Chinese Herbal
• Phenanthrolines
• 1,2,15,16-tetrahydrotanshiquinone
• tanshinaldehyde

Topics

• Animals
• Drugs, Chinese Herbal (chemistry, pharmacology)
• Leukemia P388 (pathology)
• Mice
• Phenanthrolines (chemistry, isolation & purification, pharmacology)
• Tumor Cells, Cultured (drug effects)