[Botulinum toxin in disabling dermatological diseases].

Abstract

Botulinum toxin could represent nowadays a new treatment modality especially for cutaneous conditions in course of which conventional treatments remain unsuccessful. Besides palmar and plantar hyperhidrosis, botulinum toxin has demonstrated efficacy in different conditions associated with hyperhidrosis, such as dyshidrosis, multiple eccrine hidrocystomas, hidradenitis suppurativa, Frey syndrome, but also in different conditions worsened by hyperhidrosis such as Hailey-Hailey disease, Darier disease, inversed psoriasis, aquagenic palmoplantar keratoderma, pachyonychia congenital. Moreover, different cutaneous conditions associated with sensitive disorders and/or neurological involvements could benefit from botulinum toxin, for example anal fissures, leg ulcers, lichen simplex, notalgia paresthetica, vestibulitis. Endly, a case of cutis laxa was described where the patient was improved by cutaneous injections of botulinum toxin.

• Authors: R Messikh, L Atallah, F Aubin, P Humbert
• Journal: Annales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 136 Suppl 4 Pg. S129-36 (May 2009) ISSN: 0151-9638 [Print] France
• Vernacular Title: La toxine botulique dans les maladies dermatologiques invalidantes.
• PMID: 19576479 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Dermatologic Agents
• Neuromuscular Agents
• Botulinum Toxins

Topics

• Botulinum Toxins (therapeutic use)
• Darier Disease (drug therapy)
• Dermatologic Agents (therapeutic use)
• Female
• Fissure in Ano (drug therapy)
• Hidradenitis Suppurativa (drug therapy)
• Hidrocystoma (drug therapy)
• Humans
• Hyperhidrosis (drug therapy)
• Keratoderma, Palmoplantar (drug therapy)
• Leg Ulcer (drug therapy)
• Nails, Malformed (drug therapy)
• Neurodermatitis (drug therapy)
• Neuromuscular Agents (therapeutic use)
• Paresthesia (drug therapy)
• Pemphigus, Benign Familial (drug therapy)
• Psoriasis (drug therapy)
• Sensation Disorders (drug therapy)
• Skin Diseases (drug therapy)
• Sweating, Gustatory (drug therapy)
• Treatment Outcome
• Vulvar Vestibulitis (drug therapy)