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Positron emission tomography / computerized tomography evaluation of primary Hodgkin's disease of liver.

Abstract
Occurrence of primary Hodgkin's lymphoma (PHL) of the liver is extremely rare. We report on a case of a 60-year-old male who presented with liver mass and B-symptomatology. Hepatoma or hepatic metastasis from a gastrointestinal primary was initially suspected. Tumor markers like AFP, CEA, Total PSA, and CA-19.9 were within normal limits. Positron Emission Tomography / Computerized Tomography (PET/CT) revealed a large hepatic lesion and a nodal mass in the porta hepatis. A liver biopsy was consistent with Hodgkin's lymphoma. There was complete regression of the hepatic lesion and evidence of shrinkage of the nodal mass following four cycles of chemotherapy. 18F Fluro -de-oxy Glucose (FDG) PET / CT in this case helped in establishing a primary hepatic lymphoma by demonstrating the absence of pathologically hypermetabolic foci in any other nodes or organs. PET / CT scan is a useful adjunct to conventional imaging and histopathology, not only to establish the initial diagnosis, but also to monitor treatment response in PHL.
AuthorsV S Gota, N C Purandare, S Gujral, S Shah, R Nair, V Rangarajan
JournalIndian journal of cancer (Indian J Cancer) 2009 Jul-Sep Vol. 46 Issue 3 Pg. 237-9 ISSN: 0019-509X [Print] India
PMID19574678 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
Topics
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Fluorodeoxyglucose F18
  • Hodgkin Disease (diagnostic imaging, drug therapy, pathology)
  • Humans
  • Liver Neoplasms (diagnostic imaging, drug therapy, pathology)
  • Male
  • Middle Aged
  • Positron-Emission Tomography
  • Prognosis
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed

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