Abstract | BACKGROUND: METHODS: Immunofluorescent confocal microscopy, phage binding assay, and immunohistochemical studies were used to demonstrate the receptor specificity of phage/ peptide-29. The effect of peptide-29 on the proliferation of OSCC cells was studied using 3-dimensional (3D) cell cultures. RESULTS: CONCLUSIONS: Peptide-29 selected from biopanning may have clinical potential for HNSCC.
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Authors | Jenn-Ren Hsiao, Yao Chang, Yuh-Ling Chen, Su-Huei Hsieh, Keng-Fu Hsu, Chun-Fu Wang, Sen-Tien Tsai, Ying-Tai Jin |
Journal | Head & neck
(Head Neck)
Vol. 32
Issue 2
Pg. 160-72
(Feb 2010)
ISSN: 1097-0347 [Electronic] United States |
PMID | 19572290
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright 2009 Wiley Periodicals, Inc. |
Chemical References |
- Antigens, Neoplasm
- Integrins
- Peptide Library
- Peptides
- integrin alphavbeta6
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Topics |
- Antigens, Neoplasm
(metabolism)
- Carcinoma, Squamous Cell
(metabolism)
- Cell Adhesion
- Cell Line, Tumor
- Cell Proliferation
- Enzyme-Linked Immunosorbent Assay
- Humans
- Immunohistochemistry
- Integrins
(metabolism)
- Microscopy, Confocal
- Mouth Neoplasms
(metabolism)
- Peptide Library
- Peptides
(metabolism)
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