A novel lab-on-a-tube for multimodality neuromonitoring of patients with traumatic brain injury (TBI).

Abstract

A novel lab-on-a-tube integrated with spirally-rolled pressure, temperature, oxygen and glucose microsensors is described for multimodal neuromonitoring of patients with traumatic brain injury. In addition to measuring various crucial parameters in real-time continuous formats, the newly developed device also works as an intraventricular catheter to lower the elevated intracranial pressure by draining cerebrospinal fluid.

• Authors: Chunyan Li, Pei-Ming Wu, WooSeok Jung, Chong H Ahn, Lori A Shutter, Raj K Narayan
• Journal: Lab on a chip (Lab Chip) Vol. 9 Issue 14 Pg. 1988-90 (Jul 21 2009) ISSN: 1473-0197 [Print] England
• PMID: 19568663 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Biosensing Techniques
• Brain Injuries (blood, cerebrospinal fluid, diagnosis, physiopathology)
• Humans
• Lab-On-A-Chip Devices
• Microchip Analytical Procedures (methods)
• Monitoring, Physiologic (instrumentation, methods)
• Sensitivity and Specificity
• Time Factors