Intralesional amphotericin B in a cat with refractory localised sporotrichosis.

Abstract

The present report concerns a case of sporotrichosis in a 3-year-old male crossbred cat. After 9 months of oral itraconazole (20mg/kg) therapy, all skin lesions had resolved with the exception of a single nodular lesion located on the bridge of the nose. Therefore, a combined therapy that included intralesional (IL) amphotericin B (1mg/kg) was started. The lesion resolved completely after three weekly administrations of IL amphotericin B, given in concert with oral itraconazole. The cat remains well 1 year after discontinuing therapy, with no signs of recurrence.

• Authors: Isabella D F Gremião, Tânia Maria P Schubach, Sandro A Pereira, Aline M Rodrigues, Adriana R Chaves, Mônica B L Barros
• Journal: Journal of feline medicine and surgery (J Feline Med Surg) Vol. 11 Issue 8 Pg. 720-3 (Aug 2009) ISSN: 1098-612X [Print] England
• PMID: 19553150 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antifungal Agents
• Amphotericin B

Topics

• Amphotericin B (administration & dosage)
• Animals
• Antifungal Agents (administration & dosage)
• Brazil
• Cat Diseases (drug therapy, microbiology)
• Cats
• Injections, Intralesional (veterinary)
• Male
• Nose Diseases (drug therapy, microbiology, veterinary)
• Sporotrichosis (drug therapy, veterinary)
• Treatment Outcome