Abstract | PURPOSE: METHODS: RESULTS: Oxidative activity was significantly higher in both glaucoma groups than in the cataracts group (GG vs CG, p=3.68 E-34; DG vs CG, p=5.11 E-45) and was significantly higher in GG than in DG (p=0.0034). SOD activity was significantly higher in both glaucoma groups than in the cataracts group (GG vs CG, p=1.08 E-14; DG vs CG, p=3.70 E-22), and was significantly higher in GG than in DG (p=0.018). Finally, total antioxidant status was significantly decreased in both glaucoma groups compared with the cataracts group (GG vs CG, p=2.51 E-12; DG vs CG, p=5.06 E-05), and was more significantly decreased in GG than in DG (p=9.23 E-07). CONCLUSIONS:
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Authors | Vicente Zanon-Moreno, José J Garcia-Medina, Roberto Gallego-Pinazo, Ignacio Vinuesa-Silva, Maria A Moreno-Nadal, Maria D Pinazo-Duran |
Journal | European journal of ophthalmology
(Eur J Ophthalmol)
2009 Jul-Aug
Vol. 19
Issue 4
Pg. 565-71
ISSN: 1120-6721 [Print] United States |
PMID | 19551670
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antioxidants
- Carbonic Anhydrase Inhibitors
- Sulfonamides
- Thiobarbituric Acid Reactive Substances
- Thiophenes
- Malondialdehyde
- dorzolamide
- Superoxide Dismutase
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Topics |
- Administration, Topical
- Adult
- Aged
- Aged, 80 and over
- Antioxidants
(metabolism)
- Aqueous Humor
(metabolism)
- Carbonic Anhydrase Inhibitors
(administration & dosage)
- Case-Control Studies
- Female
- Glaucoma, Open-Angle
(drug therapy, metabolism)
- Humans
- Intraocular Pressure
(drug effects)
- Male
- Malondialdehyde
(metabolism)
- Middle Aged
- Oxidative Stress
(drug effects)
- Sulfonamides
(administration & dosage)
- Superoxide Dismutase
(metabolism)
- Thiobarbituric Acid Reactive Substances
(metabolism)
- Thiophenes
(administration & dosage)
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