Abstract | OBJECTIVE: METHODS: RESULTS: As compared with the model group, the level of FSG was lower (P < 0.01) and ISI was higher (P < 0.05) after treatment in the QJHL treated group, with pancreatic islet hyperplasia and hypertrophy ameliorated significantly (P < 0.01). And these changes were similar to those in the Ros treated group (P > 0.05). Moreover, the level of GLUT2 mRNA expression in pancreas of the QJHL group increased significantly (P < 0.01), while it was unchanged in the Ros group. CONCLUSION: QJHL could reduce IR, ameliorate pathological changes of pancreas, which is possibly related with its action on increasing GLUT2 mRNA expression in the pancreas tissue.
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Authors | Ai-ping Tian, Chen-hui Zou, Su-juan Sun |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 29
Issue 3
Pg. 242-5
(Mar 2009)
ISSN: 1003-5370 [Print] China |
PMID | 19548443
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Blood Glucose
- Drugs, Chinese Herbal
- Glucose Transporter Type 2
- Insulin
- RNA, Messenger
- qianjin huanglian
- Sodium Glutamate
|
Topics |
- Animals
- Animals, Newborn
- Blood Glucose
(metabolism)
- Drugs, Chinese Herbal
(pharmacology)
- Glucose Transporter Type 2
(genetics, metabolism)
- Insulin
(blood)
- Insulin Resistance
- Mice
- Mice, Inbred ICR
- Pancreas
(metabolism, pathology)
- RNA, Messenger
(genetics, metabolism)
- Sodium Glutamate
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